TY  - BOOK
AU  - Zhang,Z.
AU  - Wang,X.
AU  - Zhu,R.
AU  - Wang,Y.
AU  - Li,B.
AU  - Ma,Y.
AU  - Yin,Y.
TI  - Synthesis and characterization of serial random and block-copolymers based on lactide and glycolide
KW  - BIOCOMPATIBILITY
KW  - BLOCK COPOLYMERS
KW  - HYDROPHILICITY
N2  - The objective of this study is to investigate the properties of poly(lactide-co-glycolide)with different composition ratios and PLGA-PEG-PLGA copolymers synthesized by ring-opening polymerization method. Their compositions, crystallization properties, thermal and degradation behaviors, hydrophilicity and biocompatibility were studied. Our results demonstrate that poly(lactide-co-glycolide)with a 90 percent lactide and PLGA-PEG-PLGA show some crystallization properties. While as the decrease of lactide content in polymers, poly(lactide-co-glycolide)become amorphous, whereas, their hydrophilicity have been improved on the contrary. Compared to poly(lactide-co-glycolide), the PLGA-PEG-PLGA copolymer has a better hydrophilicity for the existence of polyethylene glycol block. Furthermore, both these polymers display easy controlled degradation properties and good cell compatibility
UR  - https://drive.google.com/file/d/1ohtbSb4uEG0QM5JF0gqPbKUXvVEd2psg/view?usp=drivesdk
ER  -