TY  - BOOK
AU  - Lin,Y.D.
AU  - Liang,Y.D.
AU  - Liang,S.G.
AU  - Zhang,S.X.
AU  - Chi,C.S.
TI  - Synthesis of fluorine-containing natural gastrodin and its analogues
KW  - GASTRODIN
N2  - Reactions of 2,3,4,6-tetra-O-acetyl-n-D_glucopyranosyl bromide (2)with p-hydroxybenzaldehyde, trifluoromethyl and fluoro substi- tuted aniline and 2-amino-6-fluorobenzoic acid gave l-O-(Pformyl- pheny1)-2,3,4,6-tetra-O-acetyl-(3-D-glucopyranoside (3), l-N-(m- trifluoromethylphenylamino)-2,3.4.6-tetra-O-acetyl-~~-D-glucopyra- noside (ra), l-N-(2-carboxyl-3-fluorophenyl)-2,3,4,6-tetra-O-acetyl -Is-D-glucopyranoside (4b)and 1-N-(p-fluorophenyl)-N-(2,3,4,6-tetra -0-acetyl-F-D-glucopyranoside (4~)respectively. 1-0-(perfluoro-2- propoxypropionyl)-O-benzyl-2,3,4,6-tetra-O-acetyl-~~-D-glucopyrano- side (7)and l-O-(m-trifluoromethylphenylaminobenzylidene)-2,3,4,6 -tetra-0-acetyl-\j-D-glucopyranoside (8)were also prepared in sub- sequent reactions. Conversion of the acetyl group to the hydroxyl group yielded the corresponding deprotected product. The compounds formed have been characterized by analysis, IR, 1~ and lgF NMR and mass spectroscopy. The influence of phase-transfer catalysts on the reactions is discussed
UR  - https://drive.google.com/file/d/14-pZjntSy5yJlhd5WPfyzYdmkyL1Y95M/view?usp=drivesdk
ER  -