TY  - BOOK
AU  - Gianazza,E.
AU  - Banfi,C.
TI  - Post-translational quantitation by SRM/MRM: applications in cardiology
KW  - BIOMARKERS
KW  - CARDIOVASCULAR PROTEOMICS
KW  - MASS SPECTROMETRY
KW  - MULTIPLE REACTION MONITORING
KW  - POST-TRANSLATIONAL MODIFICATIONS
KW  - PROTEIN FUNCTION
KW  - SELECTED REACTION MONITORING
KW  - TARGETED PROTEOMICS
N2  - Post-translational modifications (PTMs)have an important role in the regulation of protein function, localization, and interaction with other molecules. PTMs apply a dynamic control of proteins in both physiological and pathological conditions. The study of disease-specific PTMs allows identifying potential biomarkers and developing effective drugs. Enrichment techniques combined with high-resolution mass spectrometry (MS)/MS analysis provide attractive results on PTM characterization. Selected reaction monitoring/multiple reaction monitoring (SRM/MRM)is a powerful targeted assay for the quantitation and validation of PTMs in complex biological samples
UR  - https://drive.google.com/file/d/1rpVOE-N4gYI667tsHAdVqVmYbdpcPTeI/view?usp=drivesdk
ER  -