TY  - BOOK
AU  - Kloer,D.P.
AU  - Ruch,S.
AU  - Al-Babili,S.
AU  - Beyer,P.
AU  - Schulz,G.E.
TI  - The structure of a retinal-forming carotenoid oxigenase
KW  - CAROTENOID OXYGENASE
N2  - Enzymes that produce retinal and related apocarotenoids constitute a sequence- and thus structure-related family, a member of which was analyzed by x-ray diffraction. This member is an oxygenase and contains an Fe2+-4-His arrangement at the axis of a seven-bladed ?-propeller chain fold covered by a dome formed by six large loops. The Fe2+ is accessible through a long nonpolar tunnel that holds a carotenoid derivative in one of the crystals. On binding, three consecutive double bonds of this carotenoid changed from a straight all-trans to a cranked cis-trans-cis conformation. The remaining trans bond is located at the dioxygen-ligated Fe2+ and cleaved by oxygen
UR  - https://drive.google.com/file/d/1XHMi074oCPi4cltc2APs3zZF0ll04qxt/view?usp=drivesdk
ER  -