TY - BOOK AU - Zhu,N.L. AU - Xu,X.D. AU - Hu,M.G. AU - Sun,Z.H. AU - Wu,T.Y. AU - Yuan,J.Q. AU - Ma,G.X. TI - Bioactive cassane diterpenoids from the seeds of Caesalpinia sappan KW - CAESALPINIA SAPPAN KW - CASSANE-TYPE DITERPENOID KW - ANTIMALARIAL ACTIVITY KW - ANTI-INFLAMMATORY ACTIVITIY N2 - Three new cassane-type diterpenoids named caesalppans G-I (1-3)together with three known ones (4-6), were isolated from the methanol extract of Caesalpinia sappan seeds. Their structures were determined based on spectroscopic data. Among the isolated compounds, compound 2 displayed a moderate antimalarial activity with an IC50 value of 2.4 ?M, and compound 4 showed mild anti-inflammatory activity with an IC50 value of 28.65 ?M UR - https://drive.google.com/file/d/1wrOsWSNSVvdsdhHCoa-YewSNTsrfBhsi/view?usp=drivesdk ER -