Identfication of new naphthalenones from Juglans mandshurica and evalution of their anticancer activities 

 -  Chinese Journal of Natural Medicines, 13(9), p.707-710, 2015 .
<br/><br/> Two new naphthalenone compounds were isolated from green walnut husks of Juglans mandshurica and their structures were identified as 4-butoxybutoxy-5,8-dihydroxy-3,4-dihydro-2H-naphthalen-1-one (1), 4-ethoxyethoxy-5,8-dihydroxy-3,4-dihydro-2H-naphthalen-1-one (2). Compounds 1 and 2 were named as Juglanstetralone A (1)and Juglanstetralone B (2). Compound 1 showed more significant anti-tumor activity than 2 against gastric cancer BGC-823 cells, wih the IC50 of 125.89 (g(mL(-1). 
<br/><br/><label>Subjects--Topical Terms: </label><br/>ANTICANCER ACTIVITY<br/>JUGLANS MANDSHURICA<br/>JUGLANSTETRALONE A<br/>JUGLANSTETRALONE B<br/>WALNUT HUSK