TY  - BOOK
AU  - Yu,M.
AU  - Wang,S.J.
AU  - Li,H.
AU  - Zhang,G.J.
TI  - Xanthones from the stems of Calophyllum membranaceum Gardn. et Champ.and their anti-inflammatory activity
KW  - ANTI-INFLAMMATORY ACTIVITY
KW  - CALOPHYLLUM MEMBRANACEUM GARDN. ET CHAMP
KW  - CLUSIACEAE
KW  - XANTHONE ENANTIOMERS
KW  - XANTHONES
N2  - Eighteen undescribed xanthones, including six pairs of xanthone enantiomers, three xanthones, and three xanthone glycosides, together with one pair of known xanthone enantiomers and 12 known xanthones, were isolated from the stems of Calophyllum membranaceum Gardn. et Champ. Their structures were elucidated by spectroscopic analysis, and the absolute configuration of the enantiomers was determined by using experimental and calculated electronic circular dichroism data. All compounds were screened for their anti-inflammatory effects on LPS-induced BV-2 microglial cells. Among them, six compounds showed remarkable activities with IC50 values of 7.8-36.0 µM
UR  - https://drive.google.com/file/d/1X0JwDO-4mMQRmloY-y_UtwipNCcIuCJq/view?usp=drivesdk
ER  -