TY - BOOK AU - Das,S. AU - Sathee,L. TI - miRNA mediated regulation of nitrogen response and nitrogen use efficiency of plants: the case of wheat KW - MIRNA KW - NUE KW - NITROGEN KW - NITROGEN STARVATION RESPONSE KW - WHEAT KW - CRISPR/CAS N2 - Nitrogen (N)is needed for plant growth and development and is the major limiting nutrient due to its higher demand in agricultural production globally. The use of N fertilizers has increased considerably in recent years to achieve higher cereal yields. High N inputs coupled with declining N use efficiency (NUE)result in the degradation of the environment. Plants have developed multidimensional strategies in response to changes in N availability in soil. These strategies include N stress-induced responses such as changes in gene expression patterns. Several N stress-induced genes and other regulatory factors, such as microRNAs (miRNAs), have been identified in different plant species, opening a new avenue of research in plant biology. This review presents a general overview of miRNA-mediated regulation of N response and NUE. Further, the in-silico target predictions and the predicted miRNA-gene network for nutrient metabolism/homeostasis in wheat provide novel insights. The information on N-regulated miRNAs and the differentially expressed target transcripts are necessary resources for genetic improvement of NUE by genome editing UR - https://drive.google.com/file/d/1DSWiwqMEhJbqmFXzkET_nXh3Jks5yQCU/view?usp=drivesdk ER -