TY  - BOOK
AU  - Sun,J.
AU  - Yang,X.Q.
AU  - Wan,J.L.
AU  - Han,H.L.
AU  - Zhao,Y.D.
AU  - Cai,L.
AU  - Ding,Z.T.
TI  - The antifungal metabolites isolated from maize endophytic fungus Fusarium sp. induced by OSMAC strategy
KW  - FUSARIUM SP
KW  - SECONDARY METABOLITES
KW  - ANTIFUNGAL ACTIVITY
KW  - OSMAC
N2  - Six new sesquiterpenes, fusarchlamols A-F (1, 2, 4-7); one new natural product of sesquiterpenoid, methyltricinonoate (3); and ten known compounds were found from Fusarium sp. cultured in two different media by the one strain many compounds strategy. The compounds (1, 2, and 4-11)were isolated from Fusarium sp. in PDB medium, and compounds (3-5, 8, and 10-17)were discovered from Fusarium sp. in coffee medium. Additionally, the configuration of 8 was first reported in the research by Mosher's method. The structures were established by 1D, 2D NMR, mass spectrometry, calculated ECD spectra, and Mosher's method. Compounds 1, 2, 6/7, 12, and 16 indicated significant antifungal activities against the phytopathogen Alternaria alternata isolated from Coffea arabica with MICs of 1 ?g/mL. The investigation on the anti-phytopathogen activity of metabolites can provide lead compounds for agrochemicals
UR  - https://drive.google.com/file/d/1LPKiQYhKOquhZnvecgZc208zssng054U/view?usp=drivesdk
ER  -