TY - BOOK AU - Wolters,B. AU - Eilert,U. TI - Acridonepoxidgehalte in Kalluskulturen von Ruta graveolens und ihre Steigerung durch Mischkultur mit Pilzen KW - ACRIDONE-EPOXIDE KW - CELL CULTURE KW - COCULTURE WITH FUNGI KW - PHYTOALEXIN KW - RUTA GRAVEOLENS N2 - The classic attempt to find optimum culture conditions lead to hormonautotrophic cultures and to dark grown cultures. We made the new attempt to rise the yield of rutacridone-epoxides by coculture with not hostspecific fungi. Conditions were chosen that only diffusible elicitors could influence callus tissue. 14 days of coculture mostly caused reduced acridone-epoxide content, growthrate and up to total disappearance of chlorophyll. Within 3 - 7 days of coculture some fungi induced a significant rise of acridone-epoxide content (up to 50-fold). Culture filtrates of these fungi showed comparable effects. Our results proved the acridone-epoxides to be phytoalexins. The use of fungal elicitors could be a new method to increase secondary product accumulation in tissue culture UR - https://drive.google.com/open?id=1r7QkrFXdA0wxrNMG0zdkke1UbDMWLsNT&usp=drive_copy ER -