On the reptation theory of gel electrophoresis 

 - Biopolymers, 25(3), p.431-454, 1986 .
<br/><br/> Artículo 
<br/><br/> We introduce a new biased reptation theory that allows a qualitative and semiquantitative study of DNA gel electrophoresis. We prove that stretching of the end-to-end vector of a very long charged reptating chain in an electric field occurs in a short period of time during a typical electrophoresis experiment, and that this leads to a fielddependent mobility only weaky dependent upon the size of the chain, in agreement with experiments on DNA. We also propose a practical technique to avoid chain stretching. Finally, many scaling laws are predicted, most of them being verifiable by experiment. 
<br/><br/><label>Subjects--Topical Terms: </label><br/>GEL ELECTROPHORESIS