TY - BOOK AU - Slater,G.W. AU - Noolandi,J. TI - On the reptation theory of gel electrophoresis T2 - Biopolymers, 25(3), p.431-454, 1986 KW - GEL ELECTROPHORESIS N1 - Artículo N2 - We introduce a new biased reptation theory that allows a qualitative and semiquantitative study of DNA gel electrophoresis. We prove that stretching of the end-to-end vector of a very long charged reptating chain in an electric field occurs in a short period of time during a typical electrophoresis experiment, and that this leads to a fielddependent mobility only weaky dependent upon the size of the chain, in agreement with experiments on DNA. We also propose a practical technique to avoid chain stretching. Finally, many scaling laws are predicted, most of them being verifiable by experiment UR - https://drive.google.com/file/d/16rOOD8jgbBgReGxmbUnaeUcWCe6BClD7/view?usp=drive_link ER -