TY - BOOK AU - Friedman,Herman AU - Klein,Thomas W. AU - Bendinelli,Mauro ED - SpringerLink (Online service) TI - Infectious Diseases and Substance Abuse T2 - Infectious Agents and Pathogenesis, SN - 9780306486883 U1 - 616.079 23 PY - 2005/// CY - Boston, MA PB - Springer US KW - MEDICINE KW - IMMUNOLOGY KW - EMERGING INFECTIOUS DISEASES KW - MICROBIOLOGY KW - BIOMEDICINE KW - INFECTIOUS DISEASES N1 - Effects of Cocaine and Morphine Withdrawal on the Immune Response -- Biological Links between Cannabinoids and HIV Infection -- Cannabinoids and Herpesviruses -- Cannabinoids and Susceptibility to Neurological Infection by Free-Living Amebae -- Legionella Infection and Cannabinoids -- Nicotine and Immunity -- Nicotine Receptors and Infections -- Immunomodulatory Effects of Cigarette Smoke/Nicotine -- Regulation of Chemokine and Chemokine Receptor Expression and Function by Opioids -- Morphine, Th1/Th2 Differentiation, and Susceptibility to Infection -- Immunofluorescence Detection of Anti-CD3-?-Induced Delta Opioid Receptors by Murine Splenic T Cells -- Modulation of Immune Function by Novel Opioid Receptor Ligands -- Effect of Alcohol on Microbial Infection -- Brucella Infection and Ethanol -- Alcohol, Infection, and the Lung N2 - The influence of many drugs of abuse - licit and illicit - on immune function has been examined extensively in recent years. Many such substances, including marijuana, cocaine, morphine, and nicotine, have been shown to enhance the disease process by impairing immunologic function. Use of these drugs impairs immunologic functions by suppressing antibody function, decreasing cytokine production, enhancing production and release of IL1, and suppressing IL2 and interferon. Among the viruses known to be effected by these drugs are viruses such as herpes simplex virus and murine retrovirus and bacterial agents such as Staphylococcus, Listeria, Treponema, and Legionella. This volume, part of the Infectious Agents and Pathogenesis series, examines a variety of drugs of abuse and how they affect the immune system UR - http://dx.doi.org/10.1007/b100398 ER -