TY - BOOK AU - Corley,Ronald B. ED - SpringerLink (Online service) TI - A Guide to Methods in the Biomedical Sciences SN - 9780387228457 U1 - 610 23 PY - 2005/// CY - Boston, MA PB - Springer US KW - MEDICINE KW - HUMAN GENETICS KW - BIOCHEMISTRY KW - MEDICINE & PUBLIC HEALTH KW - BIOMEDICINE GENERAL KW - MEDICAL BIOCHEMISTRY N1 - Detection and Analysis of Proteins -- Detection and Analysis of Nucleic Acids -- Recombinant DNA Techniques: Cloning and Manipulation of DNA -- Antibody-Based Techniques -- Microscopy: Imaging of Biological Specimens -- The Derivation and Manipulation of Experimental Animals in Biomedical Sciences N2 - A Guide to Methods in the Biomedical Sciences gives a basic description of common methods used in research. This is not intended to be a methods book. Rather, it is intended to be a book that outlines the purpose of the methods described, their limitations and provide alternative approaches as appropriate. Thousands of methods have been developed in the various biomedical disciplines and those covered in this book represent the basic, essential and most widely used methods in several different disciplines. The historical background (including some interesting anecdotes) leading to the development of ground-breaking techniques are described, especially those that significantly advanced the field of biomedical research. Advances that earned their inventors prestigious Nobel Prizes are emphasized. The book is divided into six sections, highlighting selected methods in protein chemistry, nucleic acids, recombinant DNA technology (including forensic based methods), antibody-based techniques, microscopy and imaging, and the use of animals in biomedical sciences UR - http://dx.doi.org/10.1007/b99813 ER -