TY - BOOK AU - Abrey,Lauren E. AU - Chamberlain,Marc C. AU - Engelhard,Herbert H. ED - SpringerLink (Online service) TI - Leptomeningeal Metastases T2 - Cancer Treatment and Research, SN - 9780387241999 U1 - 616.994 23 PY - 2005/// CY - Boston, MA PB - Springer US KW - MEDICINE KW - NEUROLOGY KW - NEUROSURGERY KW - ONCOLOGY KW - CANCER KW - SURGERY KW - MEDICINE & PUBLIC HEALTH KW - SURGICAL ONCOLOGY N1 - Anatomy and Physiology of the Leptomeninges and CSF Space -- Leptomeningeal Neoplasia: Epidemiology, Clinical Presentation, CSF Analysis and Diagnostic Imaging -- Leptomeningeal Metastases from Solid Tumors (Meningeal Carcinomatosis) -- Leptomeningeal Metastases from Leukemias and Lymphomas -- Leptomeningeal Metastasis of Primary Central Nervous System (CNS) Neoplasms -- Leptomeningeal Cancer in the Pediatric Patient -- Neurosurgical Interventions for Leptomeningeal Tumor -- Current Treatment of Leptomeningeal Metastases: Systemic Chemotherapy, Intrathecal Chemotherapy and Symptom Management -- Radiation Therapy for Leptomeningeal Cancer -- Animal Models of Leptomeningeal Cancer -- Improving the Outcome of Patients with Leptomeningeal Cancer: New Clinical Trials and Experimental Therapies N2 - Leptomeningeal Metastases provides the reader with an overview of the state-of-the-art therapy for the leptomeningeal patient with additional information on epidemiology, symptom management, new clinical trials, and current basic research in animal models for experimental therapies. "Leptomeningeal metastases remains a devastating manifestation of hematologic malignancies and solid tumors. Leading figures in the field review the pathophysiology and clinical consequences of this process. State-of-the-art treatment strategies are presented highlighting advances in current management." Steven T. Rosen, M.D. Series Editor UR - http://dx.doi.org/10.1007/b104814 ER -