TY - BOOK AU - Nógrádi,Antal ED - SpringerLink (Online service) TI - Transplantation of Neural Tissue into the Spinal Cord T2 - Neuroscience Intelligence Unit SN - 9780387326337 U1 - 612.8 23 PY - 2006/// CY - Boston, MA PB - Springer US KW - MEDICINE KW - NEUROSCIENCES KW - NEUROLOGY KW - TRANSPLANTATION OF ORGANS, TISSUES, ETC KW - NEUROBIOLOGY KW - BIOMEDICINE KW - TRANSPLANT SURGERY N1 - Anatomy and Physiology of the Spinal Cord -- Recovery of Function After Spinal Cord Injury -- Recovery of Lost Spinal Cord Function by Facilitating the Spinal Cord Circuits Below the Lesion -- Encouraging Regeneration of Host Neurons: -- Encouraging Regeneration of Host Neurons: -- Replacement of Specific Neuronal Populations in the Spinal Cord -- Replacement of Specific Populations of Cells -- Conclusion N2 - Transplantation of Neural Tissues into the Spinal Cord presents both recent and early results from various experiments where grafts of neuronal, glial and other tissues, as well as artificial materials, were placed into the spinal cord. This book is evaluates the contribution and effect of these studies to our understanding of basic neurobiological questions. This second edition of the book provides answers to many questions which could not be answered in the first edition, and accordingly all the chapters have been extensively rewritten and edited. The findings summarized in this edition show that grafted tissue can survive and thrive in a host mammal, occasionally replace some lost function and re-establish a semblance of sophisticated and complex circuitries. These new insights are among the most exciting in neurobiology, for they challenge the view that nothing can grow or regenerate in the central nervous system and give new hope that it may be possible to treat some of the incurable diseases of the CNS UR - http://dx.doi.org/10.1007/0-387-32633-2 ER -