TY - BOOK AU - Minarovits,Janos AU - Gonczol,Eva AU - Valyi-Nagy,Tibor ED - SpringerLink (Online service) TI - Latency Strategies of Herpesviruses SN - 9780387341279 U1 - 616.9101 23 PY - 2007/// CY - Boston, MA PB - Springer US KW - MEDICINE KW - IMMUNOLOGY KW - MEDICAL VIROLOGY KW - VETERINARY MEDICINE KW - MICROBIOLOGY KW - BACTERIOLOGY KW - ANIMAL GENETICS KW - BIOMEDICINE KW - VIROLOGY KW - ANIMAL GENETICS AND GENOMICS N1 - Latency Strategies of Alphaherpesviruses: Herpes Simplex Virus and Varicella-Zoster Virus Latency in Neurons -- Modulation of Apoptotic Pathways by Herpes Simplex Viruses -- Cytomegalovirus Latency -- Human Herpesvirus 6 and Human Herpesvirus 7 -- Murid Herpesvirus 4 (MuHV-4): An Animal Model for Human Gammaherpesvirus Research -- Latency Strategies of Equine Herpesviruses -- The Multifunctional Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus -- Epstein-Barr Virus N2 - Latency is a fascinating property of herpesviruses which ensures the maintenance of their genetic information in their hosts for an extended period in the absence of productive virus replication. Focusing on human herpesviruses and animal models of herpesvirus-associated human diseases, this is the first book dealing with the intricate epigenetic mechanisms (DNA methylation, histone modification, alteration of chromatin structure) that regulate latency-associated transcription. Special attention is given to immune evasion "tricks" blocking immune responses to herpesvirus infected cells and viral RNAs and proteins involved in malignant transformation. Latency Strategies of Herpesviruses is an ideal book for researchers, scientists and graduate students in the fields of virology, immunology, microbiology, bacteriology, and veterinary medicine UR - http://dx.doi.org/10.1007/978-0-387-34127-9 ER -