TY  - BOOK
AU  - Bürkle,Alexander
ED  - SpringerLink (Online service)
TI  - Poly(ADP-Ribosyl)ation
T2  - Molecular Biology Intelligence Unit
SN  - 9780387360058
U1  - 616.9041 23
PY  - 2006///
CY  - Boston, MA
PB  - Springer US
KW  - MEDICINE
KW  - HUMAN GENETICS
KW  - MICROBIOLOGY
KW  - BIOCHEMISTRY
KW  - CYTOLOGY
KW  - BIOMEDICINE
KW  - MEDICAL MICROBIOLOGY
KW  - BIOCHEMISTRY, GENERAL
KW  - CELL BIOLOGY
N1  - Enzymes in Poly(ADP-Ribose) Metabolism -- PARP-2: Structure-Function Relationship -- Targeting the Poly (ADP-Ribose) Glycohydrolase (PARG) Gene in Mammals -- DNA Damage Signaling through Poly(ADP-Ribose) -- Roles of Poly(ADP-Ribose) Metabolism in the Regulation of Centrosome Duplication and in the Maintenance of Neuronal Integrity -- Functional Interactions of PARP-1 with p53 -- Dynamic Interaction between PARP-1, PCNA and p21waf1/cip1 -- PARP-1 as Novel Coactivator of NF-?B in Inflammatory Disorders -- PARP and Epigenetic Regulation -- PARP and the Release of Apoptosis-Inducing Factor from Mitochondria -- Genome Degradation by DNAS1L3 Endonuclease -- NAD: Metabolism and Regulatory Functions -- PARP-1 and the Shape of Cell Death -- Poly(ADP-Ribose) Polymerase (PARP) and Excitotoxicity -- Poly(ADP-Ribose) Polymerase and Ischemia-Reperfusion Injury -- Role of Poly(ADP-Ribose) Polymerase Activation in the Pathogenesis of Inflammation and Circulatory Shock -- Role of Poly-ADP-Ribosylation in Cancer Development -- PARP Inhibitors and Cancer Therapy -- Poly(ADP-Ribosyl)ation and Aging
N2  - Poly(ADP-Ribosyl)ation comprises 19 chapters written by leading international experts in the field and is richly illustrated. Extensive bibliography is given in each chapter
UR  - http://dx.doi.org/10.1007/0-387-36005-0
ER  -