TY  - BOOK
AU  - Wallace,Robert G.
AU  - Wallace,Deborah
AU  - Wallace,Rodrick
ED  - SpringerLink (Online service)
TI  - Farming Human Pathogens: Ecological Resilience and Evolutionary Process 
SN  - 9780387922133
PY  - 2009///
CY  - New York, NY
PB  - Springer New York
KW  - COMPUTER SCIENCE
KW  - MEDICAL RECORDS
KW  - DATA PROCESSING
KW  - EPIDEMIOLOGY
KW  - BIOINFORMATICS
KW  - HEALTH INFORMATICS
KW  - PUBLIC HEALTH/GESUNDHEITSWESEN
KW  - COMPUTATIONAL BIOLOGY/BIOINFORMATICS
N1  - Formal theory I -- Formal theory II -- Coevolution -- Eigen's paradox -- Farming human pathogens -- Final Remarks
N2  - Farming Human Pathogens: Ecological Resilience and Evolutionary Process introduces a cutting-edge formalism based on the asymptotic limit theorems of information theory to describe how punctuated shifts in mesoscale ecosystems can entrain patterns of gene expression and organismal evolution. The development is applied to several infectious diseases that have evolved in response to the world as humans have made it. Many pathogens emerging from underneath epidemiological control are 'farmed' in the metaphorical sense, as the evolution of drug resistant HIV makes clear, but some, like avian influenza, emerge quite literally as the result of new practices in industrial farming. Effective disease control in the 21st Century must necessarily involve broad economic and social reform for reasons embedded in the basics of pathogen evolution.
UR  - http://dx.doi.org/10.1007/978-0-387-92213-3
ER  -