cCMP and cUMP come into the spotlight, finally
- Trends in Biochemical Sciences, 47(6), p.461-463, 2022 .
Artículo
cCMP and cUMP have been identified in numerous biological systems and proposed to serve as second messengers. However, this proposal remained controversial because of the base-promiscuity of generators, effectors, phosphodiesterases, and bacterial toxins. With the identification of specific cytidylyl and uridylyl cyclases, cCMP and cUMP research enters a new era.