TY - BOOK AU - Bergman,Nicholas H. TI - Comparative genomics T2 - Methods in molecular biology SN - 1588296938 (v. 1 : alk. paper) U1 - 572.86 PY - 2007/// CY - Totowa, NJ PB - Humana Press, KW - ANALISIS DE SEQUENCIA KW - METODOS KW - GENOMICA KW - INGENIERIA GENETICA KW - TECNICAS KW - METODOLOGIA EN GENOMICA KW - NUCLEOTIDOS SECUENCIA N1 - Incluye referencias bibliográficas e índices; Contenido: v.1. Genome visualization and annotation ; Sequence alignments ; Identification of conserved sequences and biases in codon usage ; Identification and structural characterization of noncoding RNAs -- v.2. Comparative analysis of domain and protein families ; Orthologs, synteny, and genome evolution ; Experimental analysis of whole genomes : analysis of copy number and sequence polymorphisms N2 - This volume provides a collection of robust protocols for molecular biologists studying comparative genomics. Each chapter includes detailed instructions for using a particular tool or method and an introduction to the theory behind the technique. Given the tremendous increase in available biosequence data over the past ten years, this volume is timely, comprehensive, and novel. Comparative Genomics, Volume 2, provides a collection of robust protocols for molecular biologists beginning to use comparative genomic analysis tools in a variety of areas. Volume 2 contains the last three of seven sections. In the second volume, the fifth section describes a number of tools for comparative analysis of domain and gene families. These tools are particularly useful for predicting protein function as well as potential protein-protein interactions. In the sixth section, methods for comparing groups of genes and gene order are discussed, as are several tools for analyzing genome evolution. Finally, the seventh section deals with experimental comparative genomics. This section includes methods for comparing gene copy number across an entire genome, comparative genomic hybridization, SNP analysis, as well as genome-wide mapping and typing systems for bacterial genomes. Given the tremendous increase in available biosequence data over the past ten years, Comparative Genomics, Volume 1, is timely, comprehensive, and novel. A companion Volume 1 is also available from Humana Press UR - https://www.cicy.mx/sitios/sib/doctoelectronico/8802.pdf ER -