000			02035nam a2200301Ia 4500
003			MX-MdCICY
005			20250625122509.0
040			_cCICY
090			_aB-6007
245	1	0	_aTranscription factors: tools to engineer the production of pharmacologically active plant metabolites
490	0		_vTrends in Pharmacological Sciences, 23(12), p.563-569, 2002
520	3		_aPlants produce a variety of secondary metabolites, some of which are used as pharmaceuticals or are health promoting as food components. Recent genetic studies on the flavonoid biosynthetic pathway show that transcription factors are efficient new molecular tools for plant metabolic engineering to increase the production of valuable compounds. The use of specific transcription factors would avoid the time-consuming step of acquiring knowledge about all enzymatic steps of a poorly characterized biosynthetic pathway. Although genetic approaches are difficult for most plant species, promoter studies of single-pathway genes and T-DNA activation tagging are feasible alternative approaches for isolating transcription factors, as illustrated for terpenoid indole alkaloid biosynthesis in Catharanthus roseus. Recent genetic studies on the flavonoid and alkaloid biosynthetic pathways show that transcription factors are efficient new molecular tools for plant metabolic engineering to increase the production of valuable pharmaceuticals.
650	1	4	_aTRANSCRIPTION FACTORS
650	1	4	_aCATHARANTHUS ROSEUS
650	1	4	_aALKALOID
650	1	4	_aMETABOLIC ENGINEERING
650	1	4	_aFLAVONOID
650	1	4	_aPHARMACEUTICAL COMPOUNDS
650	1	4	_aNUTRACEUTICAL
650	1	4	_aPLANT PHARMACEUTICAL
650	1	4	_aL COMPOUNDS
650	1	4	_aFUNCTIONAL FOOD
700	1	2	_aGantet, P.
700	1	2	_aMemelink, J.
856	4	0	_uhttps://drive.google.com/file/d/1vPi_Ud79ZoM09h8JOPjLHHKo-qpxuLhH/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942			_2Loc _cREF1
008			250602s9999 xx |||||s2 |||| ||und|d
999			_c40352 _d40352