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245 1 0 _aInventory and function of yeast ABC proteins: about sex, stress, pleiotropic drug and heavy metal resistance
490 0 _vBiochimica et Biophysica Acta (BBA)- Biomembranes , 1461(2), p.217-236, 1999
520 3 _aSaccharomyces cerevisiae was the first eukaryotic organism whose complete genome sequence has been determined, uncovering the existence of numerous genes encoding proteins of the ATP-binding cassette (ABC)family. Fungal ABC proteins are implicated in a variety of cellular functions, ranging from clinical drug resistance development, pheromone secretion, mitochondrial function, peroxisome biogenesis, translation elongation, stress response to cellular detoxification. Moreover, some yeast ABC proteins are orthologues of human disease genes, which makes yeast an excellent model system to study the molecular mechanisms of ABC protein-mediated disease. This review provides a comprehensive discussion and update on the function and transcriptional regulation of all known ABC genes from yeasts, including those discovered in fungal pathogens.
650 1 4 _aFUNGUS
650 1 4 _aABC PROTEIN
650 1 4 _aPDR NETWORK
650 1 4 _aGENE REGULATION
650 1 4 _aANTIFUNGAL DRUG RESISTANCE
650 1 4 _aPATHOGEN
650 1 4 _aPHEROMONE SECRETION
650 1 4 _aORGANELLE
650 1 4 _aSTRESS RESPONSE
650 1 4 _aCELLULAR DETOXIFICATION
700 1 2 _aBauer, B.E.
700 1 2 _aWolfger, H.
700 1 2 _aKuchler, K.
856 4 0 _uhttps://drive.google.com/file/d/1-gg8R3FUCJ-fgd-uzSJPXvi_pAdv1JKy/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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