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090 _aB-6167
245 1 0 _aA novel `two-component' protein containing histidine kinase and response regulator domains required for sporulation in Aspergillus nidulans
490 0 _vCurrent Genetics, 37(6), p.364 - 372, 2000
520 3 _aAbstract We have characterised a novel Aspergillus nidulans gene encoding a `two-component' signalling protein (tcsA). tcsA encodes both a histidine kinase domain and a response regulator domain similar to those found in bacterial, lower eukaryotic and plant members of the two-component family of proteins, while two PAS domains in the amino-terminal region of the predicted tcsA product may monitor the signal which regulates a tcsA histidine kinase-response regulator phosphorelay. While tcsA is nonessential for vegetative growth, cells lacking the gene are unable to produce conidia on standard Aspergillus growth media. However, tcsA is not absolutely required for production since this defect is suppressed by growth on 1 M sorbitol.
650 1 4 _aASPERGILLUS NIDULANS
650 1 4 _aTCSA GENE
650 1 4 _aTWO-COMPONENT SYSTEM
700 1 2 _aAppleyard, M.V.C.L.
700 1 2 _aMcPheat, W.L.
700 1 2 _aStark, M.J.R.
856 4 0 _uhttps://drive.google.com/file/d/1lS9HL9aq5WWIvBthNP3JSfDEadQtWJc7/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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