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245 1 0 _aFunctional analysis of the calcineurin-encoding gene cnaA from Aspergillus oryzae: evidence for its putative role in stress adaptation
490 0 _vArchives of MicroBiology, 179(6), p.416-422, 2003
520 3 _aThe presence of putative STRE (stress response regulatory element)and HSF (heat-shock factor)transcription factor binding sites in the promoter region of the gene encoding calcineurin (cnaA)from Aspergillus oryzae implicated a probable role for calcineurin in the stress response. The activity of calcineurin was enhanced during growth of the wild-type strain in the presence of 1 M NaCl (2.6-fold), at alkaline pH 10.0 (2.9-fold)and at 37 °C (1.6-fold). The induction of cnaA antisense expression resulted in reduced calcineurin activity (1.4-fold)and caused a growth defect under the stress conditions. Induction of a strain overexpressing cnaA resulted in an increase in calcineurin activity under stress conditions, such as the presence of 1 M NaCl (73
650 1 4 _aASPERGILLUS ORYZAE
650 1 4 _aSTRESS
650 1 4 _aCALCINEURIN A
650 1 4 _aCNAA
650 1 4 _aPROTEIN PHOSPHATASE 2B
650 1 4 _aCALMODULIN- DEPENDENT PROTEIN PHOSPHATASE
700 1 2 _aJuvvadi, P.R.
700 1 2 _aKuroki, Y.
700 1 2 _aArioka, M.
700 1 2 _aNakajima, H.
700 1 2 _aKitamoto, K.
856 4 0 _uhttps://drive.google.com/file/d/1Wzk4L9dS3iZSMA-2ZyW1QerQQnr8TCQ7/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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