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245 1 0 _aAntiplasmodial activity of four Kenyan medicinal plants
490 0 _vJournal of EthnoPharmacology, 56(2), p.133-137, 1997
520 3 _aA preliminary antiplasmodial and phytochemical screening of four Kenyan medicinal plants was carried out. The medicinal plants were extracted and tested for in vitro antiplasmodial activity against chloroquine-sensitive (K67)and chloroquine-resistant (ENT36)strains of Plasmodium falciparum. Out of 16 extracts, 12 were active against ENT36 strain while seven were active against K67 strain, that is, IC50 = 50 g/ml. The most active extracts on both strains were those of leaves of Phyllanthus reticulatus Poir. and Suregada zanzibariensis Baill. (Euphorbiaceae)with IC50 = 10 g/ml. The stembark of Terminalia spinosa Engl. (Combretaceae)and the stems of Dissotis brazzae Cogn. (Melastomataceae)had IC50 = 10 g/ml for strains K67 and ENT36, respectively. A preliminary phytochemical analysis of these plants revealed the presence of different classes of primary and secondary metabolites.
650 1 4 _aPLANT EXTRACTS
650 1 4 _aANTIPLASMODIAL
650 1 4 _aPHYTOCHEMISTRY
650 1 4 _aPLASMODIUM FALCIPARUM
650 1 4 _aPHYLLANTHUS RETICULATUS
650 1 4 _aSUREGADA ZANZIBARIENSIS
650 1 4 _aTERMINALIA SPINOSA
650 1 4 _aDISSOTIS BRAZZAE
700 1 2 _aOmulokoli, E.
700 1 2 _aKhan, B.
700 1 2 _aChhabra, S.C.
856 4 0 _uhttps://drive.google.com/file/d/1CmyGExlPud_pD0rFleKsZiEML13tLNgJ/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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