000			01448nam a2200169Ia 4500
003			MX-MdCICY
005			20250625124642.0
040			_cCICY
090			_aB-6416
245	1	0	_aHistory of antifungals
490	0		_vJournal of the American Academy of Dermatology, 23(4), p.776-778, 1990
520	3		_aUntil two to three decades ago, only a few drugs were available for the treatment of fungal infections. The status of antifungal therapy changed dramatically in the late 1960s with the introduction of newer broader spectrum agents, such as the iodinated trichlorophenols and the imidazoles, that acted by disruption of the fungal cell membrane. Some of the more recently developed broad-spectrum antifungal drugs include the triazoles terconazole, itraconazole, and fluconazole and the dimethylmorpholine amorolfine. The allylamines represent one of the newest classes of compounds shown to be effective in the management of fungal disorders. The two members of this unique chemical class that have been studied clinically, naftifine and terbinafine, are effective against a wide spectrum of fungal organisms. Terbinafine has the added advantage of both topical and oral activity.
700	1	2	_aSmith, E.B.
856	4	0	_uhttps://drive.google.com/file/d/1C-tLWBPNQX_KmLQKMUhVqq1F-f3T9Jcw/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942			_2Loc _cREF1
008			250602s9999 xx |||||s2 |||| ||und|d
999			_c40760 _d40760