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| 003 | MX-MdCICY | ||
| 005 | 20250625124650.0 | ||
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| 090 | _aB-6846 | ||
| 245 | 1 | 0 | _aThe origin of genetic information: viruses as models |
| 490 | 0 | _vGene , 135(1-2), p.37-47, 1993 | |
| 520 | 3 | _aliving entity can be described as a complex adaptive system which differs from any, however complex, chemical structure by its capability of functional self-organization based on the processing of information. If one asks, where does this information come from and what is its primary semantics, the answer is: information generates itself in feedback loops via replication and selection, the objective being 'to be or not to be'. This paper describes the theoretical framework of information-generating systems and provides experimental clues for some basic forms of genetic organization, such as molecular quasi-species, hypercyclic and compartmentalized RNA-protein assemblies. The results are primarily obtained with RNA viruses and virus-like systems. The experiments are carried out with the help of automated, computer-controlled bioreactors, called 'evolution machines', that may form the basis of a new 'evolutionary biotechnology'. | |
| 650 | 1 | 4 | _aMOLECULAR EVOLUTION |
| 650 | 1 | 4 | _aSEQUENCE SPACE |
| 650 | 1 | 4 | _aERROR THRESHOLD |
| 650 | 1 | 4 | _aSELECTION |
| 650 | 1 | 4 | _aQUASI-SPECIES |
| 650 | 1 | 4 | _aRNA VIRUSES |
| 650 | 1 | 4 | _aHYPERCYCLES |
| 650 | 1 | 4 | _aEVOLUTIONARY BIOTECHNOLOGY |
| 700 | 1 | 2 | _aEigen, M. |
| 856 | 4 | 0 |
_uhttps://drive.google.com/file/d/1Ubml1kuamgHvHe49V4icPGM1onr-AIm8/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
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