000			01717nam a2200205Ia 4500
003			MX-MdCICY
005			20250625124654.0
040			_cCICY
090			_aB-7070
245	1	0	_aAn umbra.related virus found in babaco (Vasconcellea _x heilbornii)
490	0		_vArchives of Virology, 166, p.2321-2324, 2021
520	3		_aThe complete sequence of a new viral RNA from babaco (Vasconcellea × heilbornii)was determined. The genome consisted of 4,584 nucleotides, containing two open reading frames (ORFs 1 and 2), a 9-nt-long noncoding region (NCR)at the 5' terminus, and an unusually long (1,843 nt)NCR at the 3' terminus. The presence of a potential heptameric slippery signal located 12 nt upstream the stop codon of ORF 1 suggests a -1 ribosomal frameshift mechanism for the translation of ORF 2. Sequence comparisons of ORF 2 revealed similarity to the RNA-dependent RNA polymerase (RdRp)of several umbra- and umbra-like viruses. Phylogenetic analysis of the RdRp placed the new virus in a well-supported and cohesive clade that includes umbra-like viruses reported in papaya, citrus, opuntia, maize, and sugarcane hosts. Viruses of this clade share a most recent ancestor with the umbraviruses but have different genomic features. The creation of a new genus within the family Tombusviridae is proposed for the classification of these novel viruses.
700	1	2	_aCornejo-Franco, J. F.
700	1	2	_aFlores, F.
700	1	2	_aMollov, D.
700	1	2	_aQuito-Avila, D. F
856	4	0	_uhttps://drive.google.com/file/d/1ED593kTTE911uc2MOEPU9nezZGcQaN27/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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