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245 1 0 _aDevelopment of a Simple Assay Protocol for High-Throughput Screening of Mycobacterium tuberculosis Glutamine Synthetase for the Identification of Novel Inhibitors
490 0 _vJournal of BioMolecular Screening, 10(7), p.725-729, 2005
520 3 _aMycobacterium tuberculosis glutamine synthetase (GS)is an essential enzyme involved in the pathogenicity of the organism. The screening of a compound library using a robust high-throughput screening (HTS)assay is currently thought to be the most efficient way of getting lead molecules, which are potent inhibitors for this enzyme. The authors have purified the enzyme to a >90
650 1 4 _aGLUTAMINE SYNTHETASE
650 1 4 _aHIGH-THROUGHPUT SCREENING
650 1 4 _aMYCOBACTERIUM
700 1 2 _aSingh, U.
700 1 2 _aPanchanadikar, V.
700 1 2 _aSarkar, D.
856 4 0 _uhttps://drive.google.com/file/d/1DntmzRa5b6k770E9zIHnsrXdQ-CRNyMc/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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