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245 1 0 _aEvolution, biochemistry and genetics of protein kinase C in fungi
490 0 _vCurrent Genetics, 43, p.245-254, 2003
520 3 _aFrom yeast to humans, protein kinase C is an enzyme of central importance in signal transduction processes. In baker's yeast, Saccharomyces cerevisiae, a single gene encoding Pkc1p has been identified. Mutant analyses revealed that Pkc1p function is essential to ensure cellular integrity through regulation of a specific MAP kinase cascade. Due to the involvement of different defective mammalian isozymes in various diseases and the model character of simple eukaryotes, increasing attention has been paid to the structure and regulation of the enzymes of fungal origin. This review summarizes the knowledge gathered so far.
650 1 4 _aSIGNAL TRANSDUCTION
650 1 4 _aMAP KINASE
650 1 4 _aYEAST
650 1 4 _aPROTEIN DOMAINS
650 1 4 _aREGULATION
650 1 4 _aFUNGI
700 1 2 _aHans-Peter, S.
700 1 2 _aHeinisch, J.J.
856 4 0 _uhttps://drive.google.com/file/d/1iT8J53ci64e7FYonpdUL7HY3iesdvKiP/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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