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245 1 0 _aSecondary Metabolites from Chamaedora tepejilote (Palmae)are Active against Mycobacterium tuberculosis
490 0 _vPhytotherapy Research, 19(4), p.320-322, 2005
520 3 _aDue to the emergence of multi-drug resistant Mycobacterium tuberculosis strains, there is an urgent need to search for new antimycobacterial drugs. The present work describes the bioactivity-guided fractionation of Chamaedora tepejilote hexane extract which led to the isolation and the characterization of squalene, farnesol, methylic ester of hexadecanoic acid, â -sitosterol and ursolic acid. Activity against Mycobacterium tuberculosis H37Rv, determined by radiorespirometric Bactec assay, showed ursolic acid, squalene and farnesol to produce a M. tuberculosis growth inhibition of 99
650 1 4 _aCHAMAEDORA TEPEJILOTE
650 1 4 _aPALMAE
650 1 4 _aBIOASSAY-GUIDED ISOLATION
650 1 4 _aANTIMYCOBACTERIAL COMPOUNDS
650 1 4 _aTRITERPENOIDS
650 1 4 _aURSOLIC ACID
650 1 4 _aSQUALENE
700 1 2 _aJiménez, A.
700 1 2 _aMeckes, M.
700 1 2 _aAlvarez, V.
700 1 2 _aTorres, J.
700 1 2 _aParra, R.
856 4 0 _uhttps://drive.google.com/file/d/1ovbGf7UVJn4XtrvTFAUNz9jEYXG2rJYC/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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