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003			MX-MdCICY
005			20250625124702.0
040			_cCICY
090			_aB-7509
245	1	0	_aPhotoactivated perylenequinone toxins in fungal pathogenesis of plants
490	0		_vFEMS MicroBiology, 252(2), p.197-206, 2005
520	3		_aSeveral genera of plant pathogenic fungi produce photoactivated perylenequinone toxins involved in pathogenesis of their hosts. These toxins are photosensitizers, absorbing light energy and generating reactive oxygen species that damage the membranes of the host cells. Studies with toxin-deficient mutants and on the involvement of light in symptom development have documented the importance of these toxins in successful pathogenesis of plants. This review focuses on the well studied perylenequinone toxin, cercosporin, produced by species in the genus ercospora. Significant progress has been made recently on the biosynthetic pathway of cercosporin, with the characterization of genes encoding a polyketide synthase and a major facilitator superfamily transporter, representing the first and last steps of the biosynthetic pathway, as well as important regulatory genes. In addition, the resistance of Cercospora fungi to cercosporin and to the singlet oxygen that it generates has led to the use of these fungi as models for understanding cellular resistance to photosensitizers and singlet oxygen. These studies have shown that resistance is complex, and have documented a role for transporters, transient reductive detoxification, and quenchers in cercosporin resistance.
650	1	4	_aPLANT DISEASE
650	1	4	_aNON-SPECIFIC TOXIN
650	1	4	_aACTIVE OXYGEN
650	1	4	_aPYRIDOXINE
650	1	4	_aZINC CLUSTER TRANSCRIPTION FACTOR
700	1	2	_aDaub, M.E.
700	1	2	_aHerrero, S.
700	1	2	_aChung, K-R.
856	4	0	_uhttps://drive.google.com/file/d/10CL46RSyv_ndY_Oqwoor6soPWQ0ztdTs/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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