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090 _aB-7547
245 1 0 _aTwo forms of RNA polymerase II holoenzyme display different abundance during the cell cycle
490 0 _vBioChemical and Biophysical Research Communications, 302(2), p.484-488, 2003
520 3 _aWe analyzed the composition and abundance of two forms of RNA polymerase II (pol II)holoenzyme in synchronized HeLa cells. We did not detect significant changes in pol II holoenzyme composition, but we noticed differences in the abundance of the two complexes at different stages of the cell cycle. Summarized data from several independent experiments demonstrate that pol II holoenzyme, which is purified by GST-TFIIS affinity chromatography, is more abundant during G1/S and S phases. Another form of pol II holoenzyme, which is purified by anti-CDK7 antibodies, shows relatively higher amounts in G2/M and early G1 phases.
650 1 4 _aRNA POLYMERASE
650 1 4 _aHOLOENZYME
650 1 4 _aCELL CYCLE
700 1 2 _aHolland, L.
700 1 2 _aYankulov, K.
856 4 0 _uhttps://drive.google.com/file/d/10qlW2dJ1P-uN1AyEB0EFnm5pyEedb_KZ/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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