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090			_aB-7628
245	1	0	_aPathogen Recognition and Innate Immunity
490	0		_vCell, 124(4), p.783-801, 2006
520	3		_aMicroorganisms that invade a vertebrate host are initially recognized by the innate immune system through germline-encoded pattern-recognition receptors (PRRs). Several classes of PRRs, including Toll-like receptors and cytoplasmic receptors, recognize distinct microbial components and directly activate immune cells. Exposure of immune cells to the ligands of these receptors activates intracellular signaling cascades that pidly induce the expression of a variety of overlapping and unique genes involved in the inflammatory and immune responses. New insights into innate immunity are changing the way we think about pathogenesis and the treatment of infectious diseases, allergy, and autoimmunity.
700	1	2	_aAkira, S.
700	1	2	_aUematsu, S.
700	1	2	_aTakeuchi, O.
856	4	0	_uhttps://drive.google.com/file/d/1JMtxsnaYMyvxrzjNAX7O31wEV3FlEyW2/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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