000 02436nam a2200265Ia 4500
003 MX-MdCICY
005 20250625124708.0
040 _cCICY
090 _aB-7843
245 1 0 _aProkaryote and eukaryote evolvability
490 0 _vBioSystems, 69(2-3), p.163-185, 2003
520 3 _aThe concept of evolvability covers a broad spectrum of, often contradictory, ideas. At one end of the spectrum it is equivalent to the statement that evolution is possible, at the other end are untestable post hoc explanations, such as the suggestion that current evolutionary theory cannot explain the evolution of evolvability. We examine similarities and differences in eukaryote and prokaryote evolvability, and look for explanations that are compatible with a wide range of observations. Differences in genome organisation between eukaryotes and prokaryotes meets this criterion. The single origin of replication in prokaryote chromosomes (versus multiple origins in eukaryotes)accounts for many differences because the time to replicate a prokaryote genome limits its size (and the accumulation of junk DNA). Both prokaryotes and eukaryotes appear to switch from genetic stability to genetic change in response to stress.We examine a range of stress responses, and discuss how these impact on evolvability, particularly in unicellular organisms versus complex multicellular ones. Evolvability is also limited by environmental interactions (including competition)and we describe a model that places limits on potential evolvability. Examples are given of its application to predator competition and limits to lateral gene transfer. We suggest that unicellular organisms evolve largely through a process of metabolic change, resulting in biochemical diversity. Multicellular organisms evolve largely through morphological changes, not through extensive changes to cellular biochemistry.
650 1 4 _aEVOLVABILITY
650 1 4 _aEVOLUTIONARILY-STABLE NICHE-DISCONTINUITY
650 1 4 _aEUKARYOTE EVOLUTION
650 1 4 _aPROKARYOTE EVOLUTION
650 1 4 _aPERIODICALLY-SELECTED FUNCTION
650 1 4 _aGENOME EVOLUTION
700 1 2 _aPoole, A.M.
700 1 2 _aPhillips, M.J.
700 1 2 _aPenny, D.
856 4 0 _uhttps://drive.google.com/file/d/1UrPz4cIcUog-5FT1HMrlDrdWqC2aZ0eU/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 _2Loc
_cREF1
008 250602s9999 xx |||||s2 |||| ||und|d
999 _c42156
_d42156