000			01534nam a2200229Ia 4500
003			MX-MdCICY
005			20250625124711.0
040			_cCICY
090			_aB-7988
245	1	0	_aRegulating the licensing of DNA replication origins in metazoa
490	0		_vCurrent Opinion in Cell Biology, 18(3), p.231-239, 2006
520	3		_aEukaryotic DNA replication is a highly conserved process; the proteins and sequence of events that replicate animal genomes are remarkably similar to those that replicate yeast genomes. Moreover, the assembly of prereplication complexes at DNA replication origins ('DNA licensing')is regulated in all eukaryotes so that no origin fires more than once in a single cell cycle. And yet there are significant differences between species both in the selection of replication origins and in the way in which these origins are licensed to operate. Moreover, these differences impart advantages to multicellular animals and plants that facilitate their development, such as better control over endoreduplication, flexibility in origin selection, and discrimination between quiescent and proliferative states.
700	1	2	_aDePamphilis, M.L.
700	1	2	_aBlow, J.J.
700	1	2	_aGhosh, S.
700	1	2	_aSaha, T.
700	1	2	_aNoguchi, K.
700	1	2	_aVassilev, A.
856	4	0	_uhttps://drive.google.com/file/d/1KSE81B45KbwoXCPUW05xbv-t4-LODr1Z/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942			_2Loc _cREF1
008			250602s9999 xx |||||s2 |||| ||und|d
999			_c42300 _d42300