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245	1	0	_aOxidative Stress Increases Susceptibility of Mycobacterium tuberculosis to Isoniazid
490	0		_vAntimicrobial Agents and Chemotherapy, 46(9), p.2765-2771, 2002
520	3		_aIsoniazid is a first-line antibiotic used in the treatment of infections caused by Mycobacterium tuberculosis. Isoniazid is a prodrug requiring oxidative activation by the catalase-peroxidase hemoprotein, KatG. Resistance to isoniazid can be obtained by point mutations in the katG gene, with one of the most common being a threonine-for-serine substitution at position 315 (S315T). The S315T mutation is found in more than 50
700	1	2	_aBulatovic,V.M.
700	1	2	_aWengenack, N.L.
700	1	2	_aUhl, J.R.
700	1	2	_aHall, L.
700	1	2	_aRoberts, G.D.
700	1	2	_aCockerill, F.R.
700	1	2	_aRusnak, F.
856	4	0	_uhttps://drive.google.com/file/d/1KqQfDxUEbThpLyIw2OfDv9WtWoFkd7wY/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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