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245 1 0 _aPhytotoxins from the fungus Malbranchea aurantiaca
490 0 _vPhytoChemistry, 66(9), p.1012-1016, 2005
520 3 _aBioassay-directed fractionation of an ethyl acetate extract from cultures of the fungus Malbranchea aurantiaca led to the isolation of two phytotoxic compounds, namely, 1-hydroxy-2-oxoeremophil-1(10),7(11),8(9)-trien-12(8)-olide (1)and penicillic acid (2). The structure of 1 was established by spectroscopic and X-ray crystallographic analyses. Metabolites 1 and 2 caused significant inhibition of radicle growth of Amaranthus hypochondriacus with IC50 values 6.57 and 3.86 lM, respectively. In addition, 1 inhibited activation of the calmodulin-dependent enzyme cAMP phosphodiesterase (IC50 = 10.2 lM).
650 1 4 _aMALBRANCHEA AURANTIACA
650 1 4 _aAMARANTHUS HYPOCHONDRIACUS
650 1 4 _aEREMOPHILANE
650 1 4 _aSESQUITERPENOIDS
650 1 4 _a1-HYDROXY-2-OXOEREMOPHIL-1(10),7(11),8(9)-TRIEN-12(8)-OLIDE
650 1 4 _aCALMODULIN
650 1 4 _aCAMP PHOSPHODIESTERASE
650 1 4 _aPHYTOTOXINS
700 1 2 _aMartínez-Luis, S.
700 1 2 _aGonzález, M.C.
700 1 2 _aUlloa, M.
700 1 2 _aMata, R.
856 4 0 _uhttps://drive.google.com/file/d/1szppQnIS5zjhCfc9MoKxfViWgf4tMYrn/view?usp=drive_link
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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