000			01866nam a2200289Ia 4500
003			MX-MdCICY
005			20250625124723.0
040			_cCICY
090			_aB-8572
245	1	0	_aA two-ply artificial blood vessel of polyurethane and poly(L-lactide)
490	0		_vColloid & Polymer Science, 268(1), p.2-11, 1990
520	3		_aA biodegradable microporous small-caliber vascular prosthesis has been developed that consists of two layers. The inner layer has been made highly antithrombogenic by cross-linking of a mixture of linoleic acid and an alipharic polyetherurethane with dicumylperoxide. Microporosity was introduced by adding sodiumfluoride crystals of about 5 I~m in diameter prior to cross-linking and leaching them out afterwards. The outer ply has been constructed by precipitating a (95/5)physical mixture ofpolyesterurethane and poly(L-lactide)from solution in the presence of sugar crystals with dimensions in the range 30-90 t~m which were removed by exposing the graft to water. The two-ply grafts were tested in vivo by replacing I cm of the abdominal aorta of rats. All the grafts remained patent at least up to 1 year and did not exhibit any aneurismal formarion. The inner layer was covered with endothelial cells and several layers of smooth muscle cells.
650	1	4	_aTWO-_PLY VASCULAR PROSTHESIS
650	1	4	_aBIODEGRADABLE
650	1	4	_aSALT-_LEACHING TECHNIQUE
650	1	4	_aCROSSLINKING
650	1	4	_aBLOODCOMPATIBLE
650	1	4	_aANEURISM
700	1	2	_aPennings, A.J.
700	1	2	_aKnol, K.E.
700	1	2	_aHoppen, H.J.
700	1	2	_aLeenslag, J.W.
700	1	2	_avan der Lei, B.
856	4	0	_uhttps://drive.google.com/file/d/1DLrJDZMP4SQvQjvA9IFqA-pZmfA0qTQt/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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