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245 1 0 _aSignals from Chloroplasts Converge to Regulate Nuclear Gene Expression
490 0 _vScience, 316, p.715-719, 2007
520 3 _aPlastid-to-nucleus retrograde signaling coordinates nuclear gene expression with chloroplast function and is essential for the photoautotrophic life-style of plants. Three retrograde signals have been described, but little is known of their signaling pathways. We show here that GUN1, a chloroplast-localized pentatricopeptide-repeat protein, and ABI4, an Apetala 2 (AP2)-type transcription factor, are common to all three pathways. ABI4 binds the promoter of a retrograde-regulated gene through a conserved motif found in close proximity to a light-regulatory element. We propose a model in which multiple indicators of aberrant plastid function in Arabidopsis are integrated upstream of GUN1 within plastids, which leads to ABI4- mediated repression of nuclear-encoded genes.
700 1 2 _aKoussevitzky, S.
700 1 2 _aNott, A.
700 1 2 _aMockler, T.C.
700 1 2 _aHong, F.
856 4 0 _uhttps://drive.google.com/file/d/14R7H3nDblW-omADLkrAUdl6Xw34QFrep/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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