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245 1 0 _aBetulinic Acid and Its Derivatives: A Review on their Biological Properties
490 0 _vCurrent Medicinal Chemistry, 12(6), p.657-666, 2005
520 3 _aBetulinic acid is a naturally occurring pentacyclic triterpenoid and has been shown to exhibit a variety of biological activities including inhibition of human immunodeficiency virus (HIV), antibacterial, antimalarial, antiinflammatory, anthelmintic and antioxidant properties. This article reports a survey of the literature dealing with betulinic acid related biological properties that has appeared from the 1990's to the beginning of 2003. A broad range of medical and pharmaceutical disciplines are covered, including a brief introduction about discovery, phytochemical aspects, organic synthesis, anti-HIV and cytotoxic mechanisms of action. Various structural modifications carried out and their biological and pharmacokinetic profiles are also incorporated.
650 1 4 _aBETULINIC ACID
650 1 4 _aANTI-HIV DERIVATIVES
650 1 4 _aANTI-HIV MECHANISM
650 1 4 _aANTICANCER DERIVATIVES
650 1 4 _aANTICANCER MECHANISM
650 1 4 _aANTIINFLAMMATORY
650 1 4 _aANTIMALARIAL
650 1 4 _aBIOTRANSFORMATION
700 1 2 _aYogeeswari, P.
700 1 2 _aSriram, D.
856 4 0 _uhttps://drive.google.com/file/d/1r_H_NzhjXV9Mn0ASYy2jLaGDG7kf5XbQ/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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