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| 005 | 20250625124733.0 | ||
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| 090 | _aB-9123 | ||
| 245 | 1 | 0 | _aEfficient synthesis of small molecule macroarrays: optimization of the macroarray synthesis platform and examination of microwave and conventional heating methods |
| 490 | 0 | _vTetrahedron, 62(19), p.4715-4727, 2006 | |
| 520 | 3 | _aWe report a method for the efficient construction of small molecule macroarrays using microwave-assisted SPOT-synthesis. Macroarrays of 1,3-diphenylpropenones (chalcones)were synthesized rapidly and in high purity starting from robust,Wang-linker-derivatized planar supports.We have optimized the entire chalcone macroarray construction process and evaluated the efficiency and utility of microwave-assisted reactions in array synthesis. Microwave heating was found to be most beneficial for reactions that require temperatures greater than the boiling points of the solvents. These microwave-assisted conditions permitted straightforward access to macroarrays of 2,4,6-triarylpyridines derived from the original chalcone scaffold. | |
| 700 | 1 | 2 | _aBowman, M. D. |
| 700 | 1 | 2 | _aJacobson, M. M. |
| 700 | 1 | 2 | _aPujanauski, B. J. |
| 700 | 1 | 2 | _aBlackwell, H. E. |
| 856 | 4 | 0 |
_uhttps://drive.google.com/file/d/1iFexGsctdmK02Ryc5Qku9iBp5raZ5C8l/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
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