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245 1 0 _aPrenylated Flavonoids: Pharmacology and Biotechnology
490 0 _vCurrent Medicinal Chemistry, 12(6), p.717-739, 2005
520 3 _aWithin the flavonoid class of natural products the prenylated sub-class is quite rich in structural variety and pharmacological activity. In the last twenty years a huge number of new structures has been reported, mostly from Leguminosae and Moraceae, with few coming from other genera. The presence, in different forms, of the isoprenoid chain can lead to impressive changes in biological activity, mostly attributed to an increased affinity for biological membranes and to an improved interaction with proteins. Molecules, such as xanthohumol and sophoraflavanone G, while being very structurally simple, show numerous pharmacological applications and are ideal candidates for SAR aimed to the discovery of new drugs.
700 1 2 _aBotta, B.
700 1 2 _aVitali, A.
700 1 2 _aMenendez, P.
700 1 2 _aMisiti, D.
700 1 2 _aMonache, G.D.
856 4 0 _uhttps://drive.google.com/file/d/1Y_nsV8nwecKsABgBA9iavQ4nIvNShLtK/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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