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090			_aB-9351
245	1	0	_aA Novel Fabrication Method of Macroporous Biodegradable Polymer Scaffolds Using Gas Foaming Salt as a Porogen Additive
490	0		_vJournal of Biomedical Materials Research Part B: Applied BioMaterials, 53(1), p.1-7, 2000
520	3		_aHighly open porous biodegradable poly(L-lactic acid)[PLLA]scaffolds for tissue regeneration were fabricated by using ammonium bicarbonate as an efficient gas foaming agent as well as a particulate porogen salt. A binary mixture of PLLA-solvent gel containing dispersed ammonium bicarbonate salt particles, which became a paste state, was cast in a mold and subsequently immersed in a hot water solution to permit the evolution of ammonia and carbon dioxide within the solidifying polymer matrix. This resulted in the expansion of pores within the polymer matrix to a great extent, leading to well interconnected macroporous scaffolds having mean pore diameters of around 300-400 mm, ideal for high-density cell seeding. Rat hepatocytes seeded into the scaffolds exhibited about 95
650	1	4	_aBIODEGRADABLE POLYMERS
650	1	4	_aPOLY(L-LACTIC ACID)
650	1	4	_aSCAFFOLDS
650	1	4	_aTISSUE ENGINEERING
650	1	4	_aAMMONIUM CARBONATE
700	1	2	_aNam, Y.S.
700	1	2	_aYoon, J.J.
700	1	2	_aPark, T.G.
856	4	0	_uhttps://drive.google.com/file/d/1wTAyH6URIylvVr6koKOKF_c0qVVBQ2yN/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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