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245 1 0 _aSynthesis, characterization, and cytocompatibility of elastomeric, biodegradable poly(ester-urethane)ureas based on poly(caprolactone)and putrescine
490 0 _vJournal of Biomedical Materials Research part A, 61(3), p.493-503, 2002
520 3 _aThe engineering of tissue for mechanically demanding applications in the cardiovascular system is likely to require mechanical conditioning of cell-scaffold constructs prior to their implantation. Scaffold properties amenable to such an application include high elasticity and strength coupled with controllable biodegradative and celladhesive properties. To fulfill such design criteria, we have synthesized a family of poly(ester-urethane)ureas (PEUUs)from polycaprolactone and 1,4-diisocyanatobutane. Lysine ethyl ester (Lys)or putrescine was used as chain extenders. To encourage cell adhesion, PEUUs were surface modified with radio-frequency glow discharge followed by coupling of Arg-Gly-Asp-Ser (RGDS). The synthesized PEUUs were highly flexible, with breaking strains of 660-895
650 1 4 _aBIODEGRADATION
650 1 4 _aSURFACE MODIFICATION
650 1 4 _aPOLY(ESTER-URETHANE)UREA
650 1 4 _aCELL ADHESION
650 1 4 _aRADIO FREQUENCY GLOW DISCHARGE
700 1 2 _aGuan, J.
700 1 2 _aSacks, M.S.
700 1 2 _aBeckman, E.J.
700 1 2 _aWagner, W.R.
856 4 0 _uhttps://drive.google.com/file/d/1yCORdfam7rGnUMQgmeODg_NkZUzoRTnS/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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