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090			_aB-9855
245	1	0	_aA Brief Review of Short Tandem Repeat Mutation
490	0		_vGeno. Prot. Bioinfo., 5(1), p.7-14, 2007
520	3		_aShort tandem repeats (STRs)are short tandemly repeated DNA sequences that involve a repetitive unit of 1{6 bp. Because of their olymorphisms and high muta- tion rates, STRs are widely used in biological research. Strand-slippage replication is the predominant mutation mechanism of STRs, and the stepwise mutation model is regarded as the main mutation model. STR mutation rates can be influenced by many factors. Moreover, some trinucleotide repeats are associated with human neurodegenerative diseases. In order to deepen our knowledge of these iseases and broaden STR application, it is essential to understand the STR mutation process in detail. In this review, we focus on the current known information about STR mutation.
650	1	4	_aSHORT TANDEM REPEATS
650	1	4	_aMUTATION
700	1	2	_aFan, H.
700	1	2	_aChu, J.Y.
856	4	0	_uhttps://drive.google.com/file/d/1zKIdzPRMs4Wu5upd2PDJFMfgNjqpF27N/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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