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245 1 0 _aStructure, dynamics and function of nuclear pore complexes
490 0 _vTrends in Cell Biology, 18(10), p.456-466, 2008
520 3 _aNuclear pore complexes are large aqueous channels that penetrate the nuclear envelope, thereby connecting the nuclear interior with the cytoplasm. Until recently, these macromolecular complexes were viewed as static structures, the only function of which was to control the molecular trafficking between the two compartments. It has now become evident that this simplistic scenario is inaccurate and that nuclear pore complexes are highly dynamic multiprotein assemblies involved in diverse cellular processes ranging from the organization of the cytoskeleton to gene expression. In this review, we discuss the most recent developments in the nuclearpore- complex field, focusing on the assembly, disassembly, maintenance and function of this macromolecular structure.
700 1 2 _aD'Angelo, M.A.
700 1 2 _aHetzer, M.W.
856 4 0 _uhttps://drive.google.com/file/d/13DlBgMLPDCmNb68eI2VzVjHtyI0XJfOa/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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