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| 003 | MX-MdCICY | ||
| 005 | 20250625140623.0 | ||
| 040 | _cCICY | ||
| 090 | _aB-9991 | ||
| 245 | 1 | 0 | _aInteractions of N-ethylmaleimide and aluminium fluoride with GABA B receptor function in rat neocortical slices |
| 490 | 0 | _vEuropean Journal of Pharmacology, 287(2), p.197-200, 1995 | |
| 520 | 3 | _aInteractions of N-ethylmaleimide and aluminium fluoride (AlF 4)with GABA B receptors have been examined using spontaneously discharging rat neocortical slices. The suppression of discharges by the GABA B receptor agonist baclofen (5-10 /zM)was irreversibly prevented by N-ethylmaleimide (10-50 tzM)and its analog N-phenylmaleimide (10-50 /zM), whilst superfusion of slices with NaF (10 mM)and A1C13 (100 ~M)to form a fluoroaluminate (AIF4-)complex markedly potentiated the action of baclofen. The lipoxygenase inhibitors, nordihydroguaiaretic acid (10-50/~M)and eicosatetraynoic acid (10-50/~M)or the phospholipase A 2 inhibitor bromophenacylbromide (50-100/~M)did not affect the response to baclofen. The depressant action of baclofen is evidently mediated through G-proteins, but is not dependent on arachidonic acid metabolites | |
| 650 | 1 | 4 | _aGABA B RECEPTOR |
| 650 | 1 | 4 | _aBACLOFEN |
| 650 | 1 | 4 | _aNEOCORTICAL SLICE |
| 650 | 1 | 4 | _aRAT |
| 650 | 1 | 4 | _aN-ETHYLMALEIMIDE |
| 650 | 1 | 4 | _aALUMINUM FLUORIDE |
| 650 | 1 | 4 | _aG-PROTEIN |
| 700 | 1 | 2 | _aOng, J. |
| 700 | 1 | 2 | _aKerr, D.I.B. |
| 856 | 4 | 0 |
_uhttps://drive.google.com/file/d/1OHnF-X51Igr236EQ13RHCiKkd0vTexay/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
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