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090			_aB-10446
245	1	0	_aSynthesis and anti-tumor evaluation of new trisulfide derivatives
490	0		_vBioorganic & Medicinal Chemistry Letters, 16(18), p.4826-4829, 2006
520	3		_aNew bis-aromatic and heterocyclic trisulfide derivatives 5, 7-10 were synthesized by optimizing lead dibenzyl trisulfide natural product (4)to evaluate their anti-tumor activities. Five compounds 5-7, 9, and 10 exhibited potent anti-tumor activities against eight different tumor cell lines with low cytotoxicity against HepG2. Initial SAR was discussed, and MOA of these anti-microtubule agents was suggested based on cell kinetic response patterns observed on RT-CES system.
700	1	2	_aHaoyun An
700	1	2	_aZhu, J.
700	1	2	_aWang, X.
700	1	2	_aXu, X.
856	4	0	_uhttps://drive.google.com/file/d/1fdRAxV2AzLjYfO_3eRKb1wV5A-_cOWXd/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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